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Clinical Study

Metformin and Muscle Health Recovery

Times of physical inactivity such as illness, recovery from surgery, or injury in older adults may harm muscle health. Research is needed to learn of ways to improve the muscle response to physical activity and recovery. We will determine if metformin, a diabetes drug, improves muscle recovery during physical inactivity. The information we gain may allow us to better design ways to help muscle health when older adults or those who are overweight become physically inactive and have rehabilitation.

I AM INTERESTED

For more information contact:

Micah Drummond

  micah.drummond@hsc.utah.edu
  801-213-2737

IRB#: IRB_00175808 | PI: Micah Drummond | Department: PHYSICAL THERAPY - COH | Approval Date: 2024-03-12 06:00:00
Study Categories: Orthopedic Studies | Specialties: Physical Therapy

Who can participate?

 Gender: All

 Age: Over 18 years old

 Volunteers: Healthy Volunteers

 Location: In Person


Inclusion Criteria:

  • Age 60 years and older
  • Good general medical health
  • Can tolerate at total of 4 muscle biopsies spread over as little as a 5 week period
  • Attend in person at the University of Utah
  • Can tolerate wearing a leg brace for 2 weeks

Exclusion Criteria:

  • History of heart, kidney, liver disease, or diabetes
  • History of stroke with a motor disability such as difficulty moving a part of your body
  • history of cancer
  • Currently on a weight-loss diet or drug
  • Taking metformin

Will I be paid for my time?

Yes

Last Updated: 4/5/21